Andrey V. Kozlov has graduated from Russian State Medical University with the degree of MD & Biophysics, received his PhD in Biology & Biophysics from Academy of Science of USSR (Moscow, USSR) and his habilitation in Pharmacology and Toxicology from the University of Veterinary Medicine (Vienna, Austria). Research interests are focused on the understanding of molecular mechanisms causing organ failure in critical care diseases and developing new diagnostic and therapeutic methods. Particular attention is given to the dysfunction of sub cellular organelles, such as mitochondria and endoplasmic reticulum, reactive oxygen and nitrogen species, the role of free iron metabolism and the regulation of gene expression in diverse models of inflammation, hypoxia/ischemia and trauma.
Weidinger A, Birgisdóttir L, Schäffer J, Meszaros AT, Zavadskis S, Müllebner A, Hecker M, Duvigneau JC, Sommer N, Kozlov AV (2022) Systemic Effects of mitoTEMPO upon Lipopolysaccharide Challenge Are Due to Its Antioxidant Part, While Local Effects in the Lung Are Due to Triphenylphosphonium. Antioxidants. 2022 Feb 6;11 (2): 323
Weidinger A, Müllebner A, Paier-Pourani J, Banerjee A, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H & Kozlov AV (2015). Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal, 22(7):572-586.
Dungel P, Perlinger M, Weidinger A, Redl H & Kozlov AV (2015). The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radical Biology and Medicine, 89:300-310.