As a highly dedicated PhD fellow at our research institute, Sergius research pursuits until recently were primarily focused on elucidating the role of reactive oxygen and nitrogen species in the activation mechanism of human amniotic mesenchymal stromal cells. The driving force behind this work is rooted in his conviction that a more comprehensive understanding of this mechanism can lead to a substantial enhancement of current cell-based therapies and usher in novel, ground breaking therapeutic approaches.

In addition to his primary research, Sergiu is strongly involved in various side projects dealing with critical care diseases and conditions. One of these projects revolves around trauma and haemorrhagic shock, where his primary focus is directed towards assessing the therapeutic potential of extracellular vesicles derived from Wharton’s Jelly mesenchymal stem cells. Another project in which he is deeply involved concentrates on sepsis. In this project, his primary focus lies on characterizing the long-term consequences of septic shock, specifically known as post-intensive care syndrome, with a special emphasis on associated muscle dysfunction. These diverse research initiatives highlight his dedication and our institute’s commitment to advancing scientific knowledge and improving outcomes in acute critical care conditions, including haemorrhagic traumatic shock, blunt chest trauma and sepsis.