Giuseppe Perale’s scientific and business interests are focused on regenerative medicine, tissue engineering and controlled drug delivery systems, grounding on his competencies in materials and technologies for biomedical applications and stem cells for clinical translational applications, applying on a wide spectrum of tools ranging from hybrid system design to bio-fabrication, to successfully bring new technologies and products from the lab scale to the clinics and finally into the market.
Following the so-called “nature inspired” philosophy, his research and experimental activities are devoted to theoretical investigations and development of feasible solutions for human tissues regeneration, aiming at both achieving new knowledge and developing industrially-scaled processes for applicable new generation therapeutic approaches. From an engineering perspective, his applied research is based on resorbable materials such as formulated hydrogels, biopolymers and composite materials in general. From a technological point of view, his attention is mainly given to multidisciplinary approaches to solve biomedical process engineering and to develop sustainable next generation medical devices. From a theoretic perspective, his main interests are towards principles of regenerative medicine, applied physical chemistry and transport phenomena, with a particular attention to their implications in human physiology. From a clinical point of view, his research activities are focused on regeneration of injured spinal cord (Regenera SA), bone regeneration (IBI SA), custom made solutions for personalized medicine and in vitro models for preclinical studies. Orthogonal interest to such topics is given to mathematical modelling and to the development of computational supportive tools to couple with experimental evidences, fully embracing the “safety by design” paradigm and the “3Rs” philosophy.