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David Hercher

PhD

David Hercher’s studied Molecular Biology at the University of Vienna and finished his Dr. scient. Med at the Medical University of Vienna. His main research focus is the investigation of regenerative processes after injuries with special emphasis on the nervous system. His group works on the elucidation of modes of action of mechanical stimuli on nerve tissue as well as on improving outcomes after peripheral nerve injuries with segmental tissue loss. Furthermore, he works on non-viral gene therapy and novel imaging modalities and their application in the field of regenerative medicine.

Selected Publications

Hromada C, Szwarc-Hofbauer D, Quyen Nguyen M, Tomasch J, Purtscher M, Hercher D, Teuschl-Woller AH (2024) Strain-induced bands of Büngner formation promotes axon growth in 3D tissue-engineered constructs. J Tissue Eng. 2024 Jan 18;15:20417314231220396. 
(free PDF)

Ashmwe M, Posa K, Rührnößl A, Heinzel JC, Heimel P, Mock M, Schädl B, Keibl C, Couillard-Despres S, Redl H, Mittermayr R, Hercher D (2022) Effects of Extracorporeal Shockwave Therapy on Functional Recovery and Circulating miR-375 and miR-382-5p after Subacute and Chronic Spinal Cord Contusion Injury in Rats. Biomedicines. 2022 Jul 7;10(7):1630. doi: 10.3390/biomedicines10071630. 
(free PDF)

Hromada C, Hartmann J, Oesterreicher J, Stoiber A, Daerr A, Schädl B, Priglinger E, Teuschl-Woller AH, Holnthoner W, Heinzel J, Hercher D (2022) Occurrence of Lymphangiogenesis in Peripheral Nerve Autografts Contrasts Schwann Cell-Induced Apoptosis of Lymphatic Endothelial Cells In Vitro. Biomolecules. 2022 Jun 12;12(6):820. 
(free PDF)

Heinzel JC, Oberhauser V, Keibl C, Swiadek N, Längle G, Frick H, Kolbenschlag J, Prahm C, Grillari J, Hercher D (2021) Evaluation of Functional Recovery in Rats After Median Nerve Resection and Autograft Repair Using Computerized Gait Analysis. Front Neurosci. 2021 Jan 21;14:593545. 
(free PDF)

Heinzel J, Längle G, Oberhauser V, Hausner T, Kolbenschlag J, Prahm C, Grillari J, Hercher D (2020) Use of the CatWalk gait analysis system to assess functional recovery in rodent models of peripheral nerve injury – a systematic review. J Neurosci Methods 2020 Nov 1;345:108889. 

Heinzel J, Swiadek N, Ashmwe M, Rührnößl A, Oberhauser V, Kolbenschlag J, Hercher D (2020) Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury. J Vis Exp 2020 Oct 6;(164). 

Hercher D, Redl H, Schuh CMAP (2020) Motor and sensory Schwann cell phenotype commitment is diminished by extracorporeal shockwave treatment in vitro. J Peripher Nerv Syst. 2020 Mar;25(1):32-43. 

Hercher D, Kerbl M, Schuh CMAP, Heinzel J, Gal L, Stainer M, Schmidhammer R, Hausner T, Redl H, Nógrádi A, Hacobian A. (2019) Spatiotemporal Differences in Gene Expression Between Motor and Sensory Autografts and Their Effect on Femoral Nerve Regeneration in the Rat. Front Cell Neurosci. 2019 May 8;13:182.
(free PDF)