Good Things Come in Threes – Celebrating the Latest PhD Triumphs at LBI Trauma
Cell death mechanisms in brain injuries, innovative µCT methods for spinal cord imaging, and reactive oxygen compounds and their effects on human stem cells—three outstanding PhD achievements at LBI Trauma demonstrate the diversity of our research.
Once again, we celebrate the remarkable accomplishments of three young researchers whose recent PhDs pave the way for improved diagnosis and treatment of various conditions.
Dr. Sergiu Dumitrescu graduated with his PhD from the Medical University of Vienna. In his thesis, he explored how reactive oxygen and nitrogen species connect inflammation and stem cell activation – two key processes in healing. Sergiu’s work revealed that while nitric oxide plays a limited role in activating human amniotic stem cells, reactive oxygen species produced by NOX4 are essential for their proliferation. This research deepens our understanding of tissue responses to injury and infection and may guide future regenerative strategies. Initially conducting his research in our “Molecular Basis of Organ Failure and Regeneration” group led by Andrey Kozlov, Sergiu now joins the Sepsis-Trauma-Shock Group under Marcin Osuchowski as a Postdoc. Known for his diligence, organization, and expertise in preclinical models, he is always ready to lend a hand and share his knowledge. We are thrilled to have him continue his scientific journey with us.
Dr. Annette Vaglio-Garro also defended her PhD at the Medical University of Vienna. Her thesis, titled “Cell death mechanisms induced by glutamate in brain injury” was supported by the FWF and explored the pathways of cell death in brain injury and their contribution to neurological disabilities. Annette’s research not only enhances our understanding of these complex processes but also holds significant translational potential, as we collaborate closely with clinicians to bring these insights from bench to bedside. Her passion for neuroscience and metabolism continues to inspire our efforts in developing novel treatment strategies for traumatic brain injury.
Dr. Patrick Heimel delivered an excellent PhD defensio at TU Vienna, defending his thesis on “Contrast Enhanced µCT of Peripheral Nerve and Spinal Cord.” With an h-index of 24 and over 100 research items listed on ResearchGate, Patrick’s contributions have already made a lasting impact. For over a decade, Patrick has been our Master of µCT, performing and managing imaging measurements in vitro and in vivo and playing a crucial role in countless studies – ranging from bone density and fracture healing to peripheral nerve regeneration, implant studies, dentistry, and even solving ancient riddles in archaeological samples. Patrick is indispensable to research at LBI Trauma and he will stay with us as Co-Lead of the Bioimaging Group. Patricks friends and coworkers went to great lenghts to make his defense day unforgettable, with a spinal cord cake and an epic treasure hunt across the institute. Clues were hidden in ancient tomes of knowledge and even inside Kinder Surprise eggs (to be revealed via µCT, of course), proving that science and playfulness go hand in hand.
We extend our heartfelt congratulations to Sergiu, Annette, and Patrick. Their dedication and innovative contributions not only inspire us at LBI Trauma but also push the boundaries of scientific discovery. We look forward to their continued impact on research and the advancement of healthcare.