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19 Sep 2024 by khirtenlehner

ASEV-CzeSEV 2024: Pioneering the future of extracellular vesicle research

Extracellular vesicles (EVs) and tissue regeneration go hand in hand! At the Joint Annual Meeting of the Austrian and Czech Societies for Extracellular Vesicles (ASEV-CzeSEV 2024), some of the brightest minds in EV research gathered to share their latest findings– and LBI Trauma was a key participant. The event, opened by Wolfgang Holnthoner (President of ASEV and head of Vascular Biology at LBI Trauma), Reinhard Gruber (MedUni Vienna), and CzeSEV President Vendula Pospíchalová offered a platform for scientists from Austria, the Czech Republic, and beyond to exchange ideas and foster new collaborations in this growing field.

Often described as “cellular messages in a bottle,” EVs are tiny, cell-derived particles that carry proteins, lipids, and genetic material, allowing cells to communicate with one another. Their ability to influence a wide range of cellular functions makes them invaluable in medical research, especially in regenerative medicine and tissue engineering. The ASEV-CzeSEV 2024 conference showcased groundbreaking research on the diverse applications of EVs—from enhancing nerve regeneration to designing vesicles for targeted drug delivery.

In addition to several brilliant presentations revolving around EVs (outlined below), the hands-on workshop led by Beckman Coulter Life Sciences was a major highlight of ASEV-CzeSEV 2024. Participants had the opportunity to learn cutting-edge techniques for isolating, analysing, and characterising EVs.

Beyond scientific discovery, ASEV-CzeSEV 2024 was a true testament to the sense of community and collaborative spirit that defines EV research in our countries. With the promising results presented at ASEV-CzeSEV 2024, the future of EVs in clinical applications has never looked brighter.

The broad palette of EV research at the LBI Trauma was presented in a wide range of talks:

  • Mai Quyen Nguyen“Laminin-binding extracellular vesicles derived from adipose-derived stem cells for targeted enhancement of peripheral nerve regeneration”
  • Madhusudhan Bobbili“Engineering extracellular vesicles for targeted drug delivery”
  • Jaroslaw Jacak“Single-molecule sensitive studies of actin in extracellular vesicles during cellular uptake”
  • Johannes Oesterreicher“Engineered extracellular vesicles for targeting and activation of lymphatic VEGFR-3”
  • Johannes Zipperle“Diagnostic significance and clinical utility of extracellular vesicles in critical illness”
  • Diogo Santos“Genetic engineering of the CD81 large extracellular loop for targeted delivery of mesenchymal stem cell-derived vesicles for spinal cord injury repair”
  • Wolfgang Holnthoner: “EV research in the Vascular Biology Group at LBI Trauma”
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