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AuriScaff enables full repopulation of cartilage matrix


For the treatment of articular cartilage defects, autologous cells are implanted in combination with a scaffold material which not only provides structural support but also effectively guides cellular behavior and influences the quality of the resulting matrix. Yet, studies have shown that biomaterials currently in clinical use do not mimic the architecture and composition of hyaline cartilage.

Best Abstract Award at the LBG Health Science Meeting 2018 for Susanne Drechsler


Susanne Drechsler received a best abstract award for her work “Characterization of microbial spread during abdominal sepsis by Next Generation Sequencing (NGS)” at the LBG Health Science Meeting 2018.

Sepsis is a life-threatening organ-dysfunction caused by a dys-regulated immune response to an infection. This study compared two methods for identification and characterization of bacteria in the circulation and the abdominal fluid during abdominal sepsis. Microbiology cultures, the standard method, were compared to NGS, a faster and more sensible method for detection of cell-free bacterial DNA.

Registration Deadline: 2nd INTERREG - 7th TERMIS Winterschool 2019


The 2nd INTERREG - 7th TERMIS Winterschool 2019 will take place in Radstadt, Salzburg, Austria from January 13th-16th, 2019 under the headline "Musculoskeletal Tissue Regeneration: From Mechanobiology to in Vitro/in Vivo Models and Advanced Imaging". Registration is open until December 20th

This is a great opportunity for students to get first-hand insights in performing preclinical (in vitro and in vivo) models as well as in vivo imaging. Participants are also invited to present posters on the workshop’s topic. Networking will be encouraged with team activities in a beautiful environment and ski slopes just 100 m from the meeting venue.

New habilitation: "Endothelial cells and their molecular functions in angiogenesis and vascularization”


Congratulations to Wolfgang Holnthoner, head of the endothelium and vascularization group, on his recent habilitation at the Medical University of Vienna!

In his thesis “Endothelial cells and their molecular functions in angiogenesis and vascularization”, he describes the role of endothelial cells in the formation and growth of blood and lymphatic vessels.

Lodwick Award for novel treatment of lumbar axial back pain


The Lodwick Award is presented annually to the author of the paper with the largest impact in the field of musculoskeletal radiology, medicine or physiology. This year, the award was handed to Dr. Stephan Becker (LBI Trauma in collaboration with Medimpuls) for his clinical study on the ablation of the basivertebral nerve (BVN) for the treatment of back pain, published in The Spine Journal.

The role of BH4 in T cell biology - LBI scientists publish in Nature


In cell-mediated immune responses, T cells play a central role. Their activation is associated with autoimmunity and cancer defense mechanisms. Adelheid Weidinger and Andrey Kozlov from the LBI Trauma’s Research Group for Molecular Basis of Organ Failure and Regeneration, together with the group of Josef Penninger from the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (Shane JF Cronin, first author), looked into the mechanisms regulating the activity of T-cells and discovered the critical role of tetrahydrobiopterin (BH4) in these mechanisms. Their findings have just been published in Nature.

Symposium Invitation: Medical research in Austrian companies


The AUVA research center knows the needs of trauma patients first hand and is always aiming to improve current treatments. By working together with partners in industry, the AUVA can provide a swift transition of new insights into the clinics.

On November 8th, the LBI Trauma is hosting a symposium on “Research and Industry” (“Forschung und Unternehmen – Gemeinsam für das Wohl von Unfallpatienten“) with subsequent networking buffet. In course of the event successful cooperations of the AUVA, the LBI Trauma and the economy are presented. Austrian companies, many of them associate members of the Austrian Cluster for Tissue Regeneration, offer insights into exciting projects in the field of regenerative medicine.