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Completed Projects

RejuvenateBone

Project title: “Enhancing the regeneration of bone defects in elderly: Rejuvenation of bone microenvironment” (Horizon 2020)

Bone defects resulting from traumatic injuries, tumor resection and bone diseases represent one of the most pressing health problems in the aging European population.

Currently, treatment success in elderly patients is severely limited due to the declining functionality of bone cells during aging, which results from multiple cell-intrinsic and cell-extrinsic mechanisms. The aim of our project is to develop a new multidisciplinary approach to enhance the regeneration of bone defects in elderly, based on recent advances in cellular reprogramming and tissue engineering.

NanoDetect

Fluorescence microscopy is one of the core technologies for biomedical research and diagnostics. The large diversity of microscopy applications requires sophisticated, individually adapted image processing methods that are able to process huge amounts of data, high background signals as well as low contrast images. The correct identification of objects in micro- or nanometer range is crucial for diagnosing diseases, the prognosing their progress and examining the impact of medical treatments.