Abgeschlossene Projekte

RejuvenateBone

Project title: “Enhancing the regeneration of bone defects in elderly: Rejuvenation of bone microenvironment” (Horizon 2020)

Bone defects resulting from traumatic injuries, tumor resection and bone diseases represent one of the most pressing health problems in the aging European population.

Currently, treatment success in elderly patients is severely limited due to the declining functionality of bone cells during aging, which results from multiple cell-intrinsic and cell-extrinsic mechanisms. The aim of our project is to develop a new multidisciplinary approach to enhance the regeneration of bone defects in elderly, based on recent advances in cellular reprogramming and tissue engineering.

NanoDetect

Die Fluoreszenzmikroskopie gehört zu den bedeutendsten Technologien der biomedizinischen Forschung. Die große Vielfalt mikroskopischer Methoden fordert ausgefeilte, individuell adaptierbare Methoden der Bildverarbeitung, die große Mengen an Daten, Hintergrundsignale und Bilder mit schlechtem Kontrast verarbeiten können. Die korrekte Identifikation von Objekten im Mikro- oder Nanometer-Bereich spielt eine wichtige Rolle in der Diagnose bzw. in der Prädiktion des Verlaufs von Krankheiten sowie die Bewertung des Therapieerfolgs.

Marie Curie International Reintegration Grant

Sepsis continues to be a major life-threatening condition in acute-care patients accounting for thousands of deaths annually, despite rapid progress in health care over the past decades in developed countries. The proposed project addressed the mechanisms and prevention of early mortality (SIRS) in experimental sepsis and its design focused on effective implementation of the "from bench to bedside" philosophy. The project consisted of three aims investigating acute immuno-inflammatory signalling triggered by a septic event.

Hippocrates

"HIPPOCRATES - A Hybrid Approach and Cartilage Tissue Engineering using Natural Origin Scaffolds, Progenitor Cells and Growth Factors"

Coordinator: Rui L. Reis (University of Minho, Portugal)

This Project involves 3 Universities from Germany, Porugal and North Ireland, Red Cross from Austria and 2 top European companies - Germany and Belgium. Started in January 2004.