Enhancing the regeneration of bone defects in elderly: Rejuvenation of bone microenvironment.

Running since 2014.

In course of the project RejuvenateBone, funded by the Marie Curie Individual Fellowship, we are using human induced pluripotent stem cells as a source of signaling factors and extracellular matrix to enhance the function of endogenous bone and vascular cells and to develop off-the-shelf bone tissue substitutes for bone defect healing.